Cargando…
Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury
Microglia in the penumbra shifted from M2 to M1 phenotype between 3 and 5 days after cerebral ischemia-reperfusion, which promoted local inflammation and injury. Shaoyao-Gancao Decoction (SGD) has been found to result in a significant upregulation of IL-13 in the penumbra, which has been shown to in...
Autores principales: | Lu, Juanjuan, Wang, Jie, Yu, Long, Cui, Rong, Zhang, Ying, Ding, Hanqing, Yan, Guofeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232306/ https://www.ncbi.nlm.nih.gov/pubmed/35757105 http://dx.doi.org/10.1155/2022/1707122 |
Ejemplares similares
-
Effects of Shaoyao-Gancao Decoction on Infarcted Cerebral Cortical Neurons: Suppression of the Inflammatory Response following Cerebral Ischemia-Reperfusion in a Rat Model
por: Zhang, Ying, et al.
Publicado: (2016) -
Network Pharmacology Identifies the Mechanisms of Action of Shaoyao Gancao Decoction in the Treatment of Osteoarthritis
por: Zhu, Naiqiang, et al.
Publicado: (2019) -
Quantitative Analysis of the Multicomponent and Spectrum–Effect Correlation of the Antispasmodic Activity of Shaoyao-Gancao Decoction
por: Xu, Yanli, et al.
Publicado: (2022) -
Potential Mechanisms of an Antiadenomyosis Chinese Herbal Formula Shaoyao-Gancao Decoction in Primary Cell Culture Model
por: Guan, Yong-Ge, et al.
Publicado: (2014) -
Investigation on the mechanism of Shaoyao-Gancao Decoction in the treatment of gastric carcinoma based on network pharmacology and experimental verification
por: Zhou, Xin, et al.
Publicado: (2023)