The cell cycle stage of bovine zygotes electroporated with CRISPR/Cas9-RNP affects frequency of Loss-of-heterozygosity editing events

At the embryonic level, CRISPR technologies have been used to edit genomes reliably and efficiently in various mammalian models, with Ribonucleoprotein (RNP) electroporation potentially representing a superior delivery method into mammalian zygotes. However, detailed insights of the interactions bet...

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Detalles Bibliográficos
Autores principales: Miskel, Dennis, Poirier, Mikhael, Beunink, Luisa, Rings, Franca, Held, Eva, Tholen, Ernst, Tesfaye, Dawit, Schellander, Karl, Salilew-Wondim, Dessie, Blaschka, Carina, Große-Brinkhaus, Christine, Brenig, Bertram, Hoelker, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232522/
https://www.ncbi.nlm.nih.gov/pubmed/35750764
http://dx.doi.org/10.1038/s41598-022-14699-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232522/
https://www.ncbi.nlm.nih.gov/pubmed/35750764
http://dx.doi.org/10.1038/s41598-022-14699-5

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