KDM6A missense variants hamper H3 histone demethylation in lung squamous cell carcinoma

KDM6A is the disease causative gene of type 2 Kabuki Syndrome, a rare multisystem disease; it is also a known cancer driver gene, with multiple somatic mutations found in a few cancer types. In this study, we looked at eleven missense variants in lung squamous cell carcinoma, one of the most common...

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Detalles Bibliográficos
Autores principales: Biagini, Tommaso, Petrizzelli, Francesco, Bianco, Salvatore Daniele, Liorni, Niccolò, Napoli, Alessandro, Castellana, Stefano, Luigi Vescovi, Angelo, Carella, Massimo, Caputo, Viviana, Mazza, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9232545/
https://www.ncbi.nlm.nih.gov/pubmed/35782738
http://dx.doi.org/10.1016/j.csbj.2022.06.041

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