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Effect of N-glycosylation on horseradish peroxidase structural and dynamical properties

The effect of different branching types of glycosylation on the structure and dynamics of the horseradish peroxidase (HRP) and an engineered split horseradish peroxidase (sHRP) was studied using all-atom molecular dynamics (MD) simulations. Although tertiary structures of both proteins are stable in...

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Detalles Bibliográficos
Autores principales: Škulj, Sanja, Barišić, Antun, Mutter, Natalie, Spadiut, Oliver, Barišić, Ivan, Bertoša, Branimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233188/
https://www.ncbi.nlm.nih.gov/pubmed/35782731
http://dx.doi.org/10.1016/j.csbj.2022.06.008