A Systematic Review of the Role of Runt-Related Transcription Factor 1 (RUNX1) in the Pathogenesis of Hematological Malignancies in Patients With Inherited Bone Marrow Failure Syndromes

Somatic runt-related transcription factor 1 (RUNX1) mutations are the most common mutations in various hematological malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Mono-allelic RUNX1 mutations in germline cells may cause familial platelet disorder (FPD), an in...

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Detalles Bibliográficos
Autores principales: Illango, Janan, Sreekantan Nair, Archana, Gor, Rajvi, Wijeratne Fernando, Ransirini, Malik, Mushrin, Siddiqui, Nabeel A, Hamid, Pousette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233622/
https://www.ncbi.nlm.nih.gov/pubmed/35765406
http://dx.doi.org/10.7759/cureus.25372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233622/
https://www.ncbi.nlm.nih.gov/pubmed/35765406
http://dx.doi.org/10.7759/cureus.25372

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