Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo

Malignant mesothelioma (MM) is a rare orphan aggressive neoplasia with low survival rates. Among the other signaling pathways, ErbB receptors and Hh signaling are deregulated in MM. Thus, molecules involved in these signaling pathways could be used for targeted therapy approaches. The aim of this st...

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Detalles Bibliográficos
Autores principales: Bei, Roberto, Benvenuto, Monica, Focaccetti, Chiara, Fazi, Sara, Moretti, Marta, Nardozi, Daniela, Angiolini, Valentina, Ciuffa, Sara, Cifaldi, Loredana, Carrano, Raffaele, Palumbo, Camilla, Miele, Martino Tony, Bei, Riccardo, Barillari, Giovanni, Manzari, Vittorio, De Smaele, Enrico, Modesti, Andrea, Masuelli, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233819/
https://www.ncbi.nlm.nih.gov/pubmed/35752861
http://dx.doi.org/10.1186/s12967-022-03490-9

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