Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya

Plasmodium falciparum infections remain among the leading causes of morbidity and mortality in holoendemic transmission areas. Located within region 5q31.1, the colony-stimulating factor 2 gene (CSF2) encodes granulocyte–macrophage colony-stimulating factor (GM-CSF), a hematopoietic growth factor th...

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Detalles Bibliográficos
Autores principales: Kisia, Lily E., Cheng, Qiuying, Raballah, Evans, Munde, Elly O., McMahon, Benjamin H., Hengartner, Nick W., Ong’echa, John M., Chelimo, Kiprotich, Lambert, Christophe G., Ouma, Collins, Kempaiah, Prakasha, Perkins, Douglas J., Schneider, Kristan A., Anyona, Samuel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233820/
https://www.ncbi.nlm.nih.gov/pubmed/35752805
http://dx.doi.org/10.1186/s41182-022-00432-5

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