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Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor
BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that promotes cell proliferation and immunomodulation in untransformed cells and maintains stemness of transformed cells, facilitating invasion and metastasis. Numerous point mutations in the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233852/ https://www.ncbi.nlm.nih.gov/pubmed/35752777 http://dx.doi.org/10.1186/s12860-022-00422-9 |