CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients

In a diverse cohort of cancer patients, Lyudovyk et al.(1) show that persistent COVID-19 infection is associated with weaker humoral responses and increased CD8(+) T cell responses that are ineffective in clearing virus, particularly in patients receiving B cell-depleting therapies.

Detalles Bibliográficos
Autores principales: Van Oekelen, Oliver, Parekh, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233996/
https://www.ncbi.nlm.nih.gov/pubmed/35835105
http://dx.doi.org/10.1016/j.xcrm.2022.100695
Descripción
Sumario:In a diverse cohort of cancer patients, Lyudovyk et al.(1) show that persistent COVID-19 infection is associated with weaker humoral responses and increased CD8(+) T cell responses that are ineffective in clearing virus, particularly in patients receiving B cell-depleting therapies.

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