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CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients
In a diverse cohort of cancer patients, Lyudovyk et al.(1) show that persistent COVID-19 infection is associated with weaker humoral responses and increased CD8(+) T cell responses that are ineffective in clearing virus, particularly in patients receiving B cell-depleting therapies.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233996/ https://www.ncbi.nlm.nih.gov/pubmed/35835105 http://dx.doi.org/10.1016/j.xcrm.2022.100695 |
| _version_ | 1784735930802765824 |
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| author | Van Oekelen, Oliver Parekh, Samir |
| author_facet | Van Oekelen, Oliver Parekh, Samir |
| author_sort | Van Oekelen, Oliver |
| collection | PubMed |
| description | In a diverse cohort of cancer patients, Lyudovyk et al.(1) show that persistent COVID-19 infection is associated with weaker humoral responses and increased CD8(+) T cell responses that are ineffective in clearing virus, particularly in patients receiving B cell-depleting therapies. |
| format | Online Article Text |
| id | pubmed-9233996 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-92339962022-06-27 CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients Van Oekelen, Oliver Parekh, Samir Cell Rep Med Spotlight In a diverse cohort of cancer patients, Lyudovyk et al.(1) show that persistent COVID-19 infection is associated with weaker humoral responses and increased CD8(+) T cell responses that are ineffective in clearing virus, particularly in patients receiving B cell-depleting therapies. Elsevier 2022-06-27 /pmc/articles/PMC9233996/ /pubmed/35835105 http://dx.doi.org/10.1016/j.xcrm.2022.100695 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Spotlight Van Oekelen, Oliver Parekh, Samir CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients |
| title | CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients |
| title_full | CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients |
| title_fullStr | CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients |
| title_full_unstemmed | CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients |
| title_short | CD8(+) T cells: An ineffective armor against prolonged COVID-19 in cancer patients |
| title_sort | cd8(+) t cells: an ineffective armor against prolonged covid-19 in cancer patients |
| topic | Spotlight |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233996/ https://www.ncbi.nlm.nih.gov/pubmed/35835105 http://dx.doi.org/10.1016/j.xcrm.2022.100695 |
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