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ESR1 hotspot mutations in endometrial stromal sarcoma with high-grade transformation and endocrine treatment
High-grade endometrial stromal sarcomas (HGESSs) are more aggressive and have higher rates of resistance to endocrine therapy than low-grade endometrial stromal sarcomas (LGESSs). The pathogenesis of hormonal resistance in these lesions has yet to be defined. Here we sought to histologically and gen...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234101/ https://www.ncbi.nlm.nih.gov/pubmed/34961764 http://dx.doi.org/10.1038/s41379-021-01003-5 |