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ESR1 hotspot mutations in endometrial stromal sarcoma with high-grade transformation and endocrine treatment

High-grade endometrial stromal sarcomas (HGESSs) are more aggressive and have higher rates of resistance to endocrine therapy than low-grade endometrial stromal sarcomas (LGESSs). The pathogenesis of hormonal resistance in these lesions has yet to be defined. Here we sought to histologically and gen...

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Detalles Bibliográficos
Autores principales: Dessources, Kimberly, Miller, Kathryn M, Kertowidjojo, Elizabeth, Da Cruz Paula, Arnaud, Zou, Youran, Selenica, Pier, da Silva, Edaise M, Benayed, Ryma, Ashley, Charles W, Abu-Rustum, Nadeem R, Dogan, Snjezana, Soslow, Robert A, Hensley, Martee L, Weigelt, Britta, Chiang, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234101/
https://www.ncbi.nlm.nih.gov/pubmed/34961764
http://dx.doi.org/10.1038/s41379-021-01003-5