Cargando…

c-Src–mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells

Invadopodia on cancer cells play crucial roles in tumor invasion and metastasis by degrading and remodeling the surrounding extracellular matrices and driving cell migration in complex 3D environments. Previous studies have indicated that microtubules (MTs) play a crucial role in elongation of invad...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saji, Takeshi, Nishita, Michiru, Ikeda, Kazuho, Endo, Mitsuharu, Okada, Yasushi, Minami, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234240/ https://www.ncbi.nlm.nih.gov/pubmed/35654143 http://dx.doi.org/10.1016/j.jbc.2022.102090

Ejemplares similares

Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma
por: Hawkins, Allegra G., et al.
Publicado: (2019)

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair
por: Zhu, Songli, et al.
Publicado: (2020)

The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions
por: Pichon, Xavier, et al.
Publicado: (2021)

Left-Right Asymmetry and Kinesin Superfamily Protein KIF3A: New Insights in Determination of Laterality and Mesoderm Induction by kif3A(−) (/−) Mice Analysis
por: Takeda, Sen, et al.
Publicado: (1999)

Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
por: Schoumacher, Marie, et al.
Publicado: (2010)

Hic-5 regulates Src-induced invadopodia rosette formation and organization
por: Gulvady, Anushree C., et al.
Publicado: (2019)

The Rab6-regulated KIF1C kinesin motor domain contributes to Golgi organization
por: Lee, Peter L, et al.
Publicado: (2015)

Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin
por: Wang, Weiyi, et al.
Publicado: (2017)

Novel Dendritic Kinesin Sorting Identified by Different Process Targeting of Two Related Kinesins: KIF21A and KIF21B
por: Marszalek, Joseph R., et al.
Publicado: (1999)

c-Src–Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)–Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells
por: Gianni, Davide, et al.
Publicado: (2010)

KAP is the neuronal organelle adaptor for Kinesin-2 KIF3AB and KIF3AC
por: Garbouchian, Alex, et al.
Publicado: (2022)

KIF3A accelerates KIF3C within the kinesin-2 heterodimer to generate symmetrical phosphate release rates for each processive step
por: Quinn, Sean M., et al.
Publicado: (2020)

Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation
por: Vukušić, Kruno, et al.
Publicado: (2021)

Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7
por: Yue, Yang, et al.
Publicado: (2018)

Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15
por: Malaby, Heidi L.H., et al.
Publicado: (2019)

KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors
por: Terribas, Ernest, et al.
Publicado: (2020)

The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C
por: Twelvetrees, Alison E., et al.
Publicado: (2019)

KIF1C, an RNA transporting kinesin-3, undergoes liquid-liquid phase separation through its C-terminal disordered domain
por: Geng, Qi, et al.
Publicado: (2023)

The Kinesin-12 Kif15 is a processive track-switching tetramer
por: Drechsler, Hauke, et al.
Publicado: (2014)

The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma
por: Luo, Weiwei, et al.
Publicado: (2018)

Modulation of estrogen related receptor alpha activity by the kinesin KIF17
por: Seneviratne, AM Pramodh Bandara, et al.
Publicado: (2017)

Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14
por: Benoit, Matthieu P.M.H., et al.
Publicado: (2021)

Laminin-111 peptide C16 regulates invadopodia activity of malignant cells through β1 integrin, Src and ERK 1/2
por: Siqueira, Adriane S., et al.
Publicado: (2016)

Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma
por: Bailey, Kelly M., et al.
Publicado: (2016)

LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
por: Ngan, Elaine, et al.
Publicado: (2017)

Cbl-associated protein is tyrosine phosphorylated by c-Abl and c-Src kinases
por: Fernow, Inga, et al.
Publicado: (2009)

Tyrosine 416 Is Phosphorylated in the Closed, Repressed Conformation of c-Src
por: Irtegun, Sevgi, et al.
Publicado: (2013)

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis
por: Zhang, Jia, et al.
Publicado: (2017)

AGO2 phosphorylation by c-Src kinase promotes tumorigenesis
por: Liu, Tianqi, et al.
Publicado: (2020)

Structural insights into human Kif7, a kinesin involved in Hedgehog signalling
por: Klejnot, Marta, et al.
Publicado: (2012)

Molecular Motor Proteins of the Kinesin Superfamily Proteins (KIFs): Structure, Cargo and Disease
por: Seog, Dae-Hyun, et al.
Publicado: (2004)

Autoinhibition of the kinesin-2 motor KIF17 via dual intramolecular mechanisms
por: Hammond, Jennetta W., et al.
Publicado: (2010)

TRIM3 Regulates the Motility of the Kinesin Motor Protein KIF21B
por: Labonté, Dorthe, et al.
Publicado: (2013)

Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A
por: Wang, Doudou, et al.
Publicado: (2016)

Observations on spontaneous tumor formation in mice overexpressing mitotic kinesin Kif14
por: Sishtla, Kamakshi, et al.
Publicado: (2018)

Kinesin-4 KIF21B is a potent microtubule pausing factor
por: van Riel, Wilhelmina E, et al.
Publicado: (2017)

Testis‐enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa
por: Miyata, Haruhiko, et al.
Publicado: (2020)

Hedgehog-induced ciliary trafficking of kinesin-4 motor KIF7 requires intraflagellar transport but not KIF7’s microtubule binding
por: Yue, Yang, et al.
Publicado: (2022)

Intraflagellar transport 20 promotes collective cancer cell invasion by regulating polarized organization of Golgi‐associated microtubules
por: Aoki, Tomoaki, et al.
Publicado: (2019)

Mesenchymal stem cell‐derived CXCL16 promotes progression of gastric cancer cells by STAT3‐mediated expression of Ror1
por: Ikeda, Taro, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_121idb6dnahdfu4mafpvhu8kat