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Plasma Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) in the Acute Respiratory Distress Syndrome

BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that is a mediator of the immune response to sepsis. PCSK9 is also highly expressed in pneumocytes and pulmonary endothelial cells. We hypothesized that serum PCSK9 levels would be associated with death and ICU ou...

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Detalles Bibliográficos
Autores principales: Metkus, Thomas S., Kim, Bo Soo, Jones, Steven R., Martin, Seth S., Schulman, Steven P., Leucker, Thorsten M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234242/
https://www.ncbi.nlm.nih.gov/pubmed/35770004
http://dx.doi.org/10.3389/fmed.2022.876046