C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways. Here, we performed a high-throughput screening of compounds blocking Rac1 proteasom...

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Detalles Bibliográficos
Autores principales: Wu, Yu, Mahtal, Nassim, Paillares, Eléa, Swistak, Léa, Sagadiev, Sara, Acharya, Mridu, Demeret, Caroline, Werf, Sylvie Van Der, Guivel-Benhassine, Florence, Schwartz, Olivier, Petracchini, Serena, Mettouchi, Amel, Caramelle, Lucie, Couvineau, Pierre, Thai, Robert, Barbe, Peggy, Keck, Mathilde, Brodin, Priscille, Machelart, Arnaud, Sencio, Valentin, Trottein, François, Sachse, Martin, Chicanne, Gaëtan, Payrastre, Bernard, Ville, Florian, Kreis, Victor, Popoff, Michel-Robert, Johannes, Ludger, Cintrat, Jean-Christophe, Barbier, Julien, Gillet, Daniel, Lemichez, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234246/
https://www.ncbi.nlm.nih.gov/pubmed/35769882
http://dx.doi.org/10.1016/j.isci.2022.104537

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