Motor dysfunction in Drosophila melanogaster as a biomarker for developmental neurotoxicity

Adequate alternatives to conventional animal testing are needed to study developmental neurotoxicity (DNT). Here, we used kinematic analysis to assess DNT of known (toluene (TOL) and chlorpyrifos (CPS)) and putative (β-N-methylamino-L-alanine (BMAA)) neurotoxic compounds. Drosophila melanogaster was...

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Detalles Bibliográficos
Autores principales: Cabrita, Ana, Medeiros, Alexandra M., Pereira, Telmo, Rodrigues, António Sebastião, Kranendonk, Michel, Mendes, César S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234254/
https://www.ncbi.nlm.nih.gov/pubmed/35769875
http://dx.doi.org/10.1016/j.isci.2022.104541

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