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A genome-wide association study of bronchodilator response in participants of European and African ancestry from six independent cohorts
INTRODUCTION: Bronchodilator response (BDR) is a measurement of acute bronchodilation in response to short-acting β2-agonists, with a heritability between 10 and 40%. Identifying genetic variants associated with BDR may lead to a better understanding of its complex pathophysiology. METHODS: We perfo...
Autores principales: | Gereige, Jessica D., Xu, Hanfei, Ortega, Victor E., Cho, Michael H., Liu, Ming, Sakornsakolpat, Phuwanat, Silverman, Edwin K., Beaty, Terri H., Miller, Bruce E., Bakke, Per, Gulsvik, Amund, Hersh, Craig P., Morrow, Jarrett D., Ampleford, Elizabeth J., Hawkins, Gregory A., Bleecker, Eugene R., Meyers, Deborah A., Peters, Stephen P., Celedón, Juan C., Tantisira, Kelan, Li, Jiang, Dupuis, Josée, O'Connor, George T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234425/ https://www.ncbi.nlm.nih.gov/pubmed/35769418 http://dx.doi.org/10.1183/23120541.00484-2021 |
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