Cargando…

Icariside II Restores Vascular Smooth Muscle Cell Contractile Phenotype by Enhancing the Focal Adhesion Signaling Pathway in the Rat Vascular Remodeling Model

Vascular smooth muscle cell (VSMC) phenotypic transition represents the fundamental pathophysiological alteration in the vascular remodeling process during the initiation and progression of cardiovascular diseases. Recent studies have revealed that Icariside II (ICS-II), a flavonol glycoside derived...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lv, Junyuan, Li, Xintong, Wu, Hongyu, Li, Jiayang, Luan, Boyang, Li, Yiqi, Li, Yeli, Yang, Danli, Wen, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234455/ https://www.ncbi.nlm.nih.gov/pubmed/35770073 http://dx.doi.org/10.3389/fphar.2022.897615

Ejemplares similares

Icariside II, a Naturally Occurring SIRT3 Agonist, Protects against Myocardial Infarction through the AMPK/PGC-1α/Apoptosis Signaling Pathway
por: Li, Yeli, et al.
Publicado: (2022)

BMPER Improves Vascular Remodeling and the Contractile Vascular SMC Phenotype
por: Pankratz, Franziska, et al.
Publicado: (2023)

Characterization of Contractile Machinery of Vascular Smooth Muscles in Hypertension
por: Yang, Qunhui, et al.
Publicado: (2021)

Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway
por: Li, Yiqi, et al.
Publicado: (2022)

Caveolin-3 Promotes a Vascular Smooth Muscle Contractile Phenotype
por: Gutierrez-Pajares, Jorge L., et al.
Publicado: (2015)

Regulation of PKC Autophosphorylation by Calponin in Contractile Vascular Smooth Muscle Tissue
por: Kim, Hak Rim, et al.
Publicado: (2013)

HDL regulates TGFß-receptor lipid raft partitioning, restoring contractile features of cholesterol-loaded vascular smooth muscle cells
por: Nagesh, Prashanth Thevkar, et al.
Publicado: (2023)

Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility
por: Liu, Yue-Feng, et al.
Publicado: (2020)

Luteolin Ameliorates Hypertensive Vascular Remodeling through Inhibiting the Proliferation and Migration of Vascular Smooth Muscle Cells
por: Su, Jie, et al.
Publicado: (2015)

Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics
por: Tsai, Min-Shao, et al.
Publicado: (2018)

Vascular Smooth Muscle Contractile Function Declines With Age in Skeletal Muscle Feed Arteries
por: Seawright, John W., et al.
Publicado: (2018)

Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy
por: Lyle, Melissa A., et al.
Publicado: (2017)

STIM1-dependent peripheral coupling governs the contractility of vascular smooth muscle cells
por: Krishnan, Vivek, et al.
Publicado: (2022)

Mechanism of Hypoxia-Mediated Smooth Muscle Cell Proliferation Leading to Vascular Remodeling
por: Huang, Xiaojuan, et al.
Publicado: (2022)

The role of GRIP1 and ephrin B3 in blood pressure control and vascular smooth muscle cell contractility
por: Wang, Yujia, et al.
Publicado: (2016)

Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell
por: Pucovský, Vladimír, et al.
Publicado: (2007)

Photoelasticity-based evaluation of cellular contractile force for phenotypic discrimination of vascular smooth muscle cells
por: Sugita, Shukei, et al.
Publicado: (2019)

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility
por: Pritchard, Harry A. T., et al.
Publicado: (2019)

A reduction in the vascular smooth muscle cell focal adhesion component syndecan‐4 is associated with abdominal aortic aneurysm formation
por: Hu, Jiaxin, et al.
Publicado: (2021)

Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction
por: Chen, Yuqiong, et al.
Publicado: (2020)

Engineering Smooth Muscle to Understand Extracellular Matrix Remodeling and Vascular Disease
por: Yarbrough, Danielle, et al.
Publicado: (2022)

SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodeling
por: Xu, Yue, et al.
Publicado: (2023)

C1q/TNF‐related protein 4 mediates proliferation and migration of vascular smooth muscle cells during vascular remodelling
por: Liu, Jingying, et al.
Publicado: (2023)

Antioxidant icariside II combined with insulin restores erectile function in streptozotocin-induced type 1 diabetic rats
por: Wang, Lin, et al.
Publicado: (2015)

Inducible Prmt1 ablation in adult vascular smooth muscle leads to contractile dysfunction and aortic dissection
por: Pyun, Jung-Hoon, et al.
Publicado: (2021)

Erratum to “Astaxanthin Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Oxidative Stress-Induced Mitochondrial Dysfunction”
por: Chen, Yuqiong, et al.
Publicado: (2021)

Editorial: Vascular smooth muscle cell fate and vascular remodeling: Mechanisms, therapeutic targets, and drugs, volume I
por: Wang, Qilong, et al.
Publicado: (2022)

Gasdermin D affects aortic vascular smooth muscle cell pyroptosis and Ang II-induced vascular remodeling
por: Fang, Zimin, et al.
Publicado: (2023)

Decreased vascular smooth muscle contractility in Hutchinson–Gilford Progeria Syndrome linked to defective smooth muscle myosin heavy chain expression
por: von Kleeck, Ryan, et al.
Publicado: (2021)

Focal adhesion kinase–related pathways may be suppressed by metformin in vascular smooth muscle cells in high glucose conditions
por: Soleimani, Ali Akbar, et al.
Publicado: (2022)

VEGF combined with DAPT promotes tissue regeneration and remodeling in vascular grafts
por: Yang, Tao, et al.
Publicado: (2023)

High Na(+) Salt Diet and Remodeling of Vascular Smooth Muscle and Endothelial Cells
por: Bkaily, Ghassan, et al.
Publicado: (2021)

Cellular Crosstalk between Endothelial and Smooth Muscle Cells in Vascular Wall Remodeling
por: Méndez-Barbero, Nerea, et al.
Publicado: (2021)

The vascular clock system generates the intrinsic circadian rhythm of vascular contractility
por: Saito, Toshiro
Publicado: (2016)

Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility
por: Busch, Albert, et al.
Publicado: (2021)

Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading
por: Tian, Hongyu, et al.
Publicado: (2017)

PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats
por: Zhang, Hongrong, et al.
Publicado: (2017)

NDUFA4L2 in smooth muscle promotes vascular remodeling in hypoxic pulmonary arterial hypertension
por: Liu, Yun, et al.
Publicado: (2020)

Interleukin-1β in Multifactorial Hypertension: Inflammation, Vascular Smooth Muscle Cell and Extracellular Matrix Remodeling, and Non-Coding RNA Regulation
por: Melton, Elaina, et al.
Publicado: (2021)

Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Apoptosis in Spontaneously Hypertensive Rats
por: Xiao, Fei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_m571n9mpvsl9od3m0ucdlj7vt7