Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury

Cell models of cardiac ischemia-reperfusion (IR) injury are essential to facilitate understanding, but current monolayer cell models poorly replicate the in vivo IR injury that occurs within a three-dimensional tissue. Here we show that this is for two reasons: the residual oxygen present in many ce...

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Detalles Bibliográficos
Autores principales: Gruszczyk, Anja V., Casey, Alva M., James, Andrew M., Prag, Hiran A., Burger, Nils, Bates, Georgina R., Hall, Andrew R., Allen, Fay M., Krieg, Thomas, Saeb-Parsy, Kourosh, Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234472/
https://www.ncbi.nlm.nih.gov/pubmed/35749842
http://dx.doi.org/10.1016/j.redox.2022.102368

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