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Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction

Disseminated Pasteurella multocida infection is rare and usually occurs in patients who are immunocompromised. Patients with liver cirrhosis seem to be particularly vulnerable; potentially related to cirrhosis associated immune dysfunction syndrome, frequently present in this population. While many...

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Autores principales: Rueda Prada, Libardo, Cardozo, Milena, Hudson, Ann, McDermott, Matthias, Urbina Verjel, Diana C., Dumic, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234597/
https://www.ncbi.nlm.nih.gov/pubmed/35769545
http://dx.doi.org/10.1016/j.idcr.2022.e01542
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author Rueda Prada, Libardo
Cardozo, Milena
Hudson, Ann
McDermott, Matthias
Urbina Verjel, Diana C.
Dumic, Igor
author_facet Rueda Prada, Libardo
Cardozo, Milena
Hudson, Ann
McDermott, Matthias
Urbina Verjel, Diana C.
Dumic, Igor
author_sort Rueda Prada, Libardo
collection PubMed
description Disseminated Pasteurella multocida infection is rare and usually occurs in patients who are immunocompromised. Patients with liver cirrhosis seem to be particularly vulnerable; potentially related to cirrhosis associated immune dysfunction syndrome, frequently present in this population. While many patients report pet cat or dog bites or scratches, some patients develop infection even without obvious exposure, just from being in contact with animals. We present a patient with cellulitis and spontaneous bacterial peritonitis by Pasteurella multocida in whom infection disseminated and the patient developed bacteremia that seeded in the right acromioclavicular joint. We hypothesize that the port of entry for infection in our patient was contact with a pet cat through a chronic open leg wound. The patient was treated with intravenous ceftriaxone 2 g daily for 6 weeks and attained complete recovery.
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spelling pubmed-92345972022-06-28 Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction Rueda Prada, Libardo Cardozo, Milena Hudson, Ann McDermott, Matthias Urbina Verjel, Diana C. Dumic, Igor IDCases Case Report Disseminated Pasteurella multocida infection is rare and usually occurs in patients who are immunocompromised. Patients with liver cirrhosis seem to be particularly vulnerable; potentially related to cirrhosis associated immune dysfunction syndrome, frequently present in this population. While many patients report pet cat or dog bites or scratches, some patients develop infection even without obvious exposure, just from being in contact with animals. We present a patient with cellulitis and spontaneous bacterial peritonitis by Pasteurella multocida in whom infection disseminated and the patient developed bacteremia that seeded in the right acromioclavicular joint. We hypothesize that the port of entry for infection in our patient was contact with a pet cat through a chronic open leg wound. The patient was treated with intravenous ceftriaxone 2 g daily for 6 weeks and attained complete recovery. Elsevier 2022-06-21 /pmc/articles/PMC9234597/ /pubmed/35769545 http://dx.doi.org/10.1016/j.idcr.2022.e01542 Text en © 2022 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Rueda Prada, Libardo
Cardozo, Milena
Hudson, Ann
McDermott, Matthias
Urbina Verjel, Diana C.
Dumic, Igor
Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction
title Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction
title_full Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction
title_fullStr Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction
title_full_unstemmed Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction
title_short Disseminated Pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – The role of cirrhosis-associated immune dysfunction
title_sort disseminated pasteurella multocida in a patient with liver cirrhosis and spontaneous bacterial peritonitis – the role of cirrhosis-associated immune dysfunction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234597/
https://www.ncbi.nlm.nih.gov/pubmed/35769545
http://dx.doi.org/10.1016/j.idcr.2022.e01542
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