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Type II BMP and activin receptors BMPR2 and ACVR2A share a conserved mode of growth factor recognition

BMPR2 is a type II Transforming Growth Factor (TGF)-β family receptor that is fundamentally associated with pulmonary arterial hypertension (PAH) in humans. BMPR2 shares functional similarities with the type II activin receptors ACVR2A and ACVR2B, as it interacts with an overlapping group of TGF-β f...

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Detalles Bibliográficos
Autores principales:	Chu, Kit-Yee, Malik, Anjali, Thamilselvan, Vijayalakshmi, Martinez-Hackert, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234707/ https://www.ncbi.nlm.nih.gov/pubmed/35643319 http://dx.doi.org/10.1016/j.jbc.2022.102076

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