Dendritic peptide-conjugated polymeric nanovectors for non-toxic delivery of plasmid DNA and enhanced non-viral transfection of immune cells

Plasmid DNA (pDNA) transfection is advantageous for gene therapies requiring larger genetic elements, including “all-in-one” CRISPR/Cas9 plasmids, but is limited by toxicity as well as poor intracellular release and transfection efficiency in immune cell populations. Here, we developed a synthetic n...

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Detalles Bibliográficos
Autores principales: Yi, Sijia, Kim, Sun-Young, Vincent, Michael P., Yuk, Simseok A., Bobbala, Sharan, Du, Fanfan, Scott, Evan Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234717/
https://www.ncbi.nlm.nih.gov/pubmed/35769884
http://dx.doi.org/10.1016/j.isci.2022.104555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234717/
https://www.ncbi.nlm.nih.gov/pubmed/35769884
http://dx.doi.org/10.1016/j.isci.2022.104555

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