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HLA-II Alleles Influence Physical and Behavioral Responses to a Whey Allergen in a Transgenic Mouse Model of Cow's Milk Allergy

The symptoms of food allergies vary significantly between individuals, likely due to genetic determinants. In humans, allergy development is initiated by antigen-presenting cells via class II human leukocyte antigen (HLA-II). The HLA-II gene is highly polymorphic, and its allelic variance is thought...

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Detalles Bibliográficos
Autores principales: Germundson, Danielle L., Nookala, Suba, Smith, Nicholas A., Warda, Yassmine, Nagamoto-Combs, Kumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234862/
https://www.ncbi.nlm.nih.gov/pubmed/35769584
http://dx.doi.org/10.3389/falgy.2022.870513