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Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report

Bacterial infection represents a turning point in the natural history of cirrhosis, causing the development of acute-on-chronic liver failure. It significantly affects the outcome of patients listed for liver transplantation. We report the case of a 57-year-old man who had been regularly treated for...

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Autores principales: Noh, Byeong Gwan, Lee, Nuri, Lee, Byoung Chul, Yoon, Myunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Transplantation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235450/
https://www.ncbi.nlm.nih.gov/pubmed/35769247
http://dx.doi.org/10.4285/kjt.21.0013
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author Noh, Byeong Gwan
Lee, Nuri
Lee, Byoung Chul
Yoon, Myunghee
author_facet Noh, Byeong Gwan
Lee, Nuri
Lee, Byoung Chul
Yoon, Myunghee
author_sort Noh, Byeong Gwan
collection PubMed
description Bacterial infection represents a turning point in the natural history of cirrhosis, causing the development of acute-on-chronic liver failure. It significantly affects the outcome of patients listed for liver transplantation. We report the case of a 57-year-old man who had been regularly treated for hepatitis B virus, alcoholic liver cirrhosis, and hepatic failure. The patient was hospitalized again due to variceal bleeding and hepatic coma. He visited the emergency room with painful anal swelling, dysuria, icteric sclera, and serious abdominal distension. The painful anal swelling and necrosis progressed; thus, he was diagnosed with Fournier’s gangrene. Enterococcus faecium and Candida albicans were detected in the blood. Gangrene wound debris was studied extensively. Despite appropriate antibiotic treatment, vancomycin-resistant enterococcus and C. albicans were continuously present in the blood. Wide debridement of the wound and T-colostomy were performed. After this, norepinephrine and vasopressin were used to maintain stable vital signs. It was difficult to establish a liver transplant operation. Despite repeated bleeding, bacterial infections improved with additional antibiotics. Finally, selected deceased donor liver transplantation in controlled Fournier’s gangrene was successfully performed. Controlled infections may be allowed in transplantation surgery.
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spelling pubmed-92354502022-06-28 Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report Noh, Byeong Gwan Lee, Nuri Lee, Byoung Chul Yoon, Myunghee Korean J Transplant Case Report Bacterial infection represents a turning point in the natural history of cirrhosis, causing the development of acute-on-chronic liver failure. It significantly affects the outcome of patients listed for liver transplantation. We report the case of a 57-year-old man who had been regularly treated for hepatitis B virus, alcoholic liver cirrhosis, and hepatic failure. The patient was hospitalized again due to variceal bleeding and hepatic coma. He visited the emergency room with painful anal swelling, dysuria, icteric sclera, and serious abdominal distension. The painful anal swelling and necrosis progressed; thus, he was diagnosed with Fournier’s gangrene. Enterococcus faecium and Candida albicans were detected in the blood. Gangrene wound debris was studied extensively. Despite appropriate antibiotic treatment, vancomycin-resistant enterococcus and C. albicans were continuously present in the blood. Wide debridement of the wound and T-colostomy were performed. After this, norepinephrine and vasopressin were used to maintain stable vital signs. It was difficult to establish a liver transplant operation. Despite repeated bleeding, bacterial infections improved with additional antibiotics. Finally, selected deceased donor liver transplantation in controlled Fournier’s gangrene was successfully performed. Controlled infections may be allowed in transplantation surgery. The Korean Society for Transplantation 2021-09-30 2021-09-30 /pmc/articles/PMC9235450/ /pubmed/35769247 http://dx.doi.org/10.4285/kjt.21.0013 Text en Copyright © 2021 The Korean Society for Transplantation https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Noh, Byeong Gwan
Lee, Nuri
Lee, Byoung Chul
Yoon, Myunghee
Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report
title Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report
title_full Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report
title_fullStr Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report
title_full_unstemmed Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report
title_short Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report
title_sort selected deceased donor liver transplantation in controlled fournier’s gangrene: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235450/
https://www.ncbi.nlm.nih.gov/pubmed/35769247
http://dx.doi.org/10.4285/kjt.21.0013
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