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CALDERA: finding all significant de Bruijn subgraphs for bacterial GWAS

MOTIVATION: Genome-wide association studies (GWAS), aiming to find genetic variants associated with a trait, have widely been used on bacteria to identify genetic determinants of drug resistance or hypervirulence. Recent bacterial GWAS methods usually rely on k-mers, whose presence in a genome can d...

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Detalles Bibliográficos
Autores principales: Roux de Bézieux, Hector, Lima, Leandro, Perraudeau, Fanny, Mary, Arnaud, Dudoit, Sandrine, Jacob, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235473/
https://www.ncbi.nlm.nih.gov/pubmed/35758804
http://dx.doi.org/10.1093/bioinformatics/btac238