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DeepMHCII: a novel binding core-aware deep interaction model for accurate MHC-II peptide binding affinity prediction

MOTIVATION: Computationally predicting major histocompatibility complex (MHC)-peptide binding affinity is an important problem in immunological bioinformatics. Recent cutting-edge deep learning-based methods for this problem are unable to achieve satisfactory performance for MHC class II molecules....

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Detalles Bibliográficos
Autores principales: You, Ronghui, Qu, Wei, Mamitsuka, Hiroshi, Zhu, Shanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235502/
https://www.ncbi.nlm.nih.gov/pubmed/35758790
http://dx.doi.org/10.1093/bioinformatics/btac225