Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis

Heterozygous mutations in SNRPB, an essential core component of the five small ribonucleoprotein particles of the spliceosome, are responsible for cerebrocostomandibular syndrome (CCMS). We show that Snrpb heterozygous mouse embryos arrest shortly after implantation. Additionally, heterozygous delet...

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Detalles Bibliográficos
Autores principales: Alam, Sabrina Shameen, Kumar, Shruti, Beauchamp, Marie-Claude, Bareke, Eric, Boucher, Alexia, Nzirorera, Nadine, Dong, Yanchen, Padilla, Reinnier, Zhang, Si Jing, Majewski, Jacek, Jerome-Majewska, Loydie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235875/
https://www.ncbi.nlm.nih.gov/pubmed/35593225
http://dx.doi.org/10.1242/dmm.049544

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