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Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity

High fat diet (HFD)-induced obesity leads to perturbation in the storage function of white adipose tissue (WAT) resulting in deposition of lipids in tissues ill-equipped to deal with this challenge. The role of insulin like growth factor-1 (IGF-1) in the systemic and organ-specific responses to HFD...

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Detalles Bibliográficos
Autores principales: Imrie, Helen, Viswambharan, Hema, Haywood, Natalie J, Bridge, Katherine I, Yuldasheva, Nadira Y, Galloway, Stacey, Simmons, Katie J, Cubbon, Richard M, Sukumar, Piruthivi, Watt, Nicole T, Lichtenstein, Laeticia, Wyatt, Judy I, Kudo, Hiromi, Goldin, Robert, Rode, Baptiste, Wheatcroft, Stephen B, Kearney, Mark T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235901/
https://www.ncbi.nlm.nih.gov/pubmed/35734881
http://dx.doi.org/10.1080/21623945.2022.2089394

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