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Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion
TMEM16F, a Ca(2+)-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear. Here, using trophoblasts as a model for cell fusion, we dem...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236608/ https://www.ncbi.nlm.nih.gov/pubmed/35670667 http://dx.doi.org/10.7554/eLife.78840 |