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Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case

Cancer is a major cause of morbidity and mortality worldwide, with squamous cell carcinoma (SCC) being the most common type. Even though SCC is the major type of cancer found in the head and neck region, the salivary glands contribute to about 1/20 cases, of which 1/10 are said to be carcinoma ex pl...

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Autores principales: Umar, Zaryab, Ilyas, Usman, Alshamam, Mohsen S, Foster, Allison, Bhangal, Rubal, Ahmed, Nazaakat, Idrees, Zarwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236687/
https://www.ncbi.nlm.nih.gov/pubmed/35774722
http://dx.doi.org/10.7759/cureus.25357
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author Umar, Zaryab
Ilyas, Usman
Alshamam, Mohsen S
Foster, Allison
Bhangal, Rubal
Ahmed, Nazaakat
Idrees, Zarwa
author_facet Umar, Zaryab
Ilyas, Usman
Alshamam, Mohsen S
Foster, Allison
Bhangal, Rubal
Ahmed, Nazaakat
Idrees, Zarwa
author_sort Umar, Zaryab
collection PubMed
description Cancer is a major cause of morbidity and mortality worldwide, with squamous cell carcinoma (SCC) being the most common type. Even though SCC is the major type of cancer found in the head and neck region, the salivary glands contribute to about 1/20 cases, of which 1/10 are said to be carcinoma ex pleomorphic adenoma (CXPA) type, and the parotid gland is found to be the most common origin of such cases. Although it usually arises later in life, it can grow rapidly, with local symptoms being late findings, if any. Even though fine needle aspiration cytology has low sensitivity for diagnosing such cancer, multiple/repeated biopsies can increase the yield and the accuracy of the test. Surgical resection is the main choice for treatment with postoperative radiation for select cases. Our case presented with CXPA with distant metastasis to multiple sites.
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spelling pubmed-92366872022-06-29 Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case Umar, Zaryab Ilyas, Usman Alshamam, Mohsen S Foster, Allison Bhangal, Rubal Ahmed, Nazaakat Idrees, Zarwa Cureus Internal Medicine Cancer is a major cause of morbidity and mortality worldwide, with squamous cell carcinoma (SCC) being the most common type. Even though SCC is the major type of cancer found in the head and neck region, the salivary glands contribute to about 1/20 cases, of which 1/10 are said to be carcinoma ex pleomorphic adenoma (CXPA) type, and the parotid gland is found to be the most common origin of such cases. Although it usually arises later in life, it can grow rapidly, with local symptoms being late findings, if any. Even though fine needle aspiration cytology has low sensitivity for diagnosing such cancer, multiple/repeated biopsies can increase the yield and the accuracy of the test. Surgical resection is the main choice for treatment with postoperative radiation for select cases. Our case presented with CXPA with distant metastasis to multiple sites. Cureus 2022-05-26 /pmc/articles/PMC9236687/ /pubmed/35774722 http://dx.doi.org/10.7759/cureus.25357 Text en Copyright © 2022, Umar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Umar, Zaryab
Ilyas, Usman
Alshamam, Mohsen S
Foster, Allison
Bhangal, Rubal
Ahmed, Nazaakat
Idrees, Zarwa
Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case
title Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case
title_full Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case
title_fullStr Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case
title_full_unstemmed Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case
title_short Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland: A Rare Case
title_sort carcinoma ex pleomorphic adenoma of the parotid gland: a rare case
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236687/
https://www.ncbi.nlm.nih.gov/pubmed/35774722
http://dx.doi.org/10.7759/cureus.25357
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