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Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl

Leukemia is a malignant hematologic neoplastic disease in which acquired mutations and genetic abnormalities in early hematopoietic precursors cause rapid proliferation of white blood cells (WBC). Acute myeloid leukemia (AML), a subtype of leukemia, is a rare form of cancer that typically manifests...

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Autores principales: Hersi, Reem M, Aldosari, Ayat M, Naaman, Nada K, Alrajhi, Rawan K, Alqahtani, Abdullah S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236691/
https://www.ncbi.nlm.nih.gov/pubmed/35774669
http://dx.doi.org/10.7759/cureus.25413
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author Hersi, Reem M
Aldosari, Ayat M
Naaman, Nada K
Alrajhi, Rawan K
Alqahtani, Abdullah S
author_facet Hersi, Reem M
Aldosari, Ayat M
Naaman, Nada K
Alrajhi, Rawan K
Alqahtani, Abdullah S
author_sort Hersi, Reem M
collection PubMed
description Leukemia is a malignant hematologic neoplastic disease in which acquired mutations and genetic abnormalities in early hematopoietic precursors cause rapid proliferation of white blood cells (WBC). Acute myeloid leukemia (AML), a subtype of leukemia, is a rare form of cancer that typically manifests in adulthood. Symptoms typically arise due to abnormal proliferation of WBC. Ocular manifestations of such malignancies are rare and they occur more commonly in acute lymphoblastic leukemia (ALL) rather than AML. Furthermore, ophthalmic involvement usually is either a sign of central nervous system involvement or disease relapse. In this article, we report the case of a 14-year-old girl who presented initially with double vision and right eye squint. The patient was later diagnosed with AML with leptomeningeal involvement.
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spelling pubmed-92366912022-06-29 Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl Hersi, Reem M Aldosari, Ayat M Naaman, Nada K Alrajhi, Rawan K Alqahtani, Abdullah S Cureus Ophthalmology Leukemia is a malignant hematologic neoplastic disease in which acquired mutations and genetic abnormalities in early hematopoietic precursors cause rapid proliferation of white blood cells (WBC). Acute myeloid leukemia (AML), a subtype of leukemia, is a rare form of cancer that typically manifests in adulthood. Symptoms typically arise due to abnormal proliferation of WBC. Ocular manifestations of such malignancies are rare and they occur more commonly in acute lymphoblastic leukemia (ALL) rather than AML. Furthermore, ophthalmic involvement usually is either a sign of central nervous system involvement or disease relapse. In this article, we report the case of a 14-year-old girl who presented initially with double vision and right eye squint. The patient was later diagnosed with AML with leptomeningeal involvement. Cureus 2022-05-27 /pmc/articles/PMC9236691/ /pubmed/35774669 http://dx.doi.org/10.7759/cureus.25413 Text en Copyright © 2022, Hersi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Hersi, Reem M
Aldosari, Ayat M
Naaman, Nada K
Alrajhi, Rawan K
Alqahtani, Abdullah S
Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl
title Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl
title_full Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl
title_fullStr Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl
title_full_unstemmed Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl
title_short Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl
title_sort bilateral papilledema and right esotropia as an initial presentation of acute myeloid leukemia in a young girl
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236691/
https://www.ncbi.nlm.nih.gov/pubmed/35774669
http://dx.doi.org/10.7759/cureus.25413
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