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Aldehyde Dehydrogenase 2 (ALDH2) Elicits Protection against Pulmonary Hypertension via Inhibition of ERK1/2-Mediated Autophagy

Pulmonary hypertension (PH) is caused by chronic hypoxia that induces the migration and proliferation of pulmonary arterial smooth muscle cells (PASMCs), eventually resulting in right heart failure. PH has been related to aberrant autophagy; however, the hidden mechanisms are still unclear. Approxim...

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Detalles Bibliográficos
Autores principales: Chang, Suchi, Wu, Jian, Jin, Jifu, Shi, Huairui, Gao, Rifeng, Li, Xiao, Jia, Daile, Sun, Xiaolei, Ou, Tiantong, Yang, Ji'e, Sun, Aijun, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236760/
https://www.ncbi.nlm.nih.gov/pubmed/35770049
http://dx.doi.org/10.1155/2022/2555476

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