Cargando…

Triptolide Induces Liver Injury by Regulating Macrophage Recruitment and Polarization via the Nrf2 Signaling Pathway

Triptolide (TP) has limited usage in clinical practice due to its side effects and toxicity, especially liver injury. Hepatic macrophages, key player of liver innate immunity, were found to be recruited and activated by TP in our previous study. The nuclear factor-erythroid-2-related factor 2 (Nrf2)...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Li, Zhang, Xi, Xing, Xin, Mohammed, Ismail, Xu, Xiao-ting, Jiang, Zhen-zhou, Wang, Tao, Huang, Xin, Wang, Xin-zhi, Zhang, Lu-yong, Sun, Li-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236772/
https://www.ncbi.nlm.nih.gov/pubmed/35770044
http://dx.doi.org/10.1155/2022/1492239