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Inhibition of DEK Enhances Doxorubicin-Induced Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia Cells

T-cell acute lymphoblastic leukemia (T-ALL) is a serious hematological tumor derived from early T-cell progenitors, which is extremely resistant to chemotherapy. Classically, doxorubicin (DOX) is an effective first-line drug for the treatment of T-ALL; however, DOX resistance limits its clinical eff...

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Detalles Bibliográficos
Autores principales: Tian, Xiaoxue, Zhu, Zeyu, Wang, Guangming, Xu, Jun, Liang, Aibin, Zhang, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236779/
https://www.ncbi.nlm.nih.gov/pubmed/35769815
http://dx.doi.org/10.1155/2022/9312971