Cargando…

MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice

Nonalcoholic steatohepatitis (NASH) is the common liver disease characterized by hepatic steatosis, inflammation, and fibrosis; there are no approved drugs to treat this disease because of incomplete understanding of pathophysiological mechanisms of NASH. Milk fat globule-epidermal growth factor-fac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jun, Du, Hui, Yuan, Yinglin, Guo, Peipei, Yang, Junxia, Yin, Xinru, Liu, Jin, Wu, Shengwang, Wan, Jingyuan, Gong, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236848/ https://www.ncbi.nlm.nih.gov/pubmed/35769208 http://dx.doi.org/10.1155/2022/5791915

Ejemplares similares

PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis
por: Jin, Kangpeng, et al.
Publicado: (2020)

PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis: Erratum
por: Jin, Kangpeng, et al.
Publicado: (2022)

Sesamin Protects against APAP-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Inflammatory Response via Deactivation of HMGB1/TLR4/NFκB Signal in Mice
por: Du, Hui, et al.
Publicado: (2023)

Extracts of Salvia-Nelumbinis Naturalis Ameliorate Nonalcoholic Steatohepatitis via Inhibiting Gut-Derived Endotoxin Mediated TLR4/NF-κB Activation
por: Shu, Xiangbing, et al.
Publicado: (2017)

Palmitoyltransferase ZDHHC3 Aggravates Nonalcoholic Steatohepatitis by Targeting S‐Palmitoylated IRHOM2
por: Xu, Minxuan, et al.
Publicado: (2023)

CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis
por: Willy, Jeffrey A., et al.
Publicado: (2015)

Osteoprotegerin deficiency aggravates methionine–choline-deficient diet-induced nonalcoholic steatohepatitis in mice
por: Wu, Shaobo, et al.
Publicado: (2023)

Hepatocellular loss of mTOR aggravates tumor burden in nonalcoholic steatohepatitis-related HCC
por: Kroh, Andreas, et al.
Publicado: (2023)

Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder
por: Hu, Junjian, et al.
Publicado: (2020)

A Case of Nonalcoholic Steatohepatitis in Central Precocious Puberty Aggravated by Gonadotropin-releasing Hormone Analog
por: Sasaki, Yoshiaki, et al.
Publicado: (2020)

Probiotics suppress nonalcoholic steatohepatitis and carcinogenesis progression in hepatocyte-specific PTEN knockout mice
por: Arai, Naoshi, et al.
Publicado: (2022)

PINCH1 knockout aggravates myocardial infarction in mice via mediating the NF-κB signaling pathway
por: Wang, Xuejun, et al.
Publicado: (2022)

15-keto-PGE(2) alleviates nonalcoholic steatohepatitis through its covalent modification of NF-κB factors
por: Hee, Siow-Wey, et al.
Publicado: (2023)

Liver-specific deletion of RORα aggravates diet-induced nonalcoholic steatohepatitis by inducing mitochondrial dysfunction
por: Kim, Hyeon-Ji, et al.
Publicado: (2017)

TNF-Like Ligand 1 Aberrance Aggravates Nonalcoholic Steatohepatitis via M1 Macrophage Polarization
por: Luo, Yuxin, et al.
Publicado: (2021)

Necroptosis in Nonalcoholic Steatohepatitis
por: Gautheron, Jérémie, et al.
Publicado: (2015)

Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway
por: Qu, Xiao-qin, et al.
Publicado: (2022)

Effects of Soothing Liver and Invigorating Spleen Recipes on the IKKβ-NF-κB Signaling Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis Rats
por: Gong, Xiang-Wen, et al.
Publicado: (2015)

Neurogenesis in Neurodegenerative Diseases: Role of MFG-E8
por: Cheyuo, Cletus, et al.
Publicado: (2019)

Palmitoyltransferase ZDHHC3 Aggravates Nonalcoholic Steatohepatitis by Targeting S‐Palmitoylated IRHOM2 (Adv. Sci. 28/2023)
por: Xu, Minxuan, et al.
Publicado: (2023)

Relationship between IL-8 Circulating Levels and TLR2 Hepatic Expression in Women with Morbid Obesity and Nonalcoholic Steatohepatitis
por: Auguet, Teresa, et al.
Publicado: (2020)

Apoptosis and diagnosis of nonalcoholic steatohepatitis
por: Kim, Chang Wook, et al.
Publicado: (2011)

Antioxidant Therapy in Nonalcoholic Steatohepatitis
por: Al-Busafi, Said A., et al.
Publicado: (2012)

The Immune Landscape in Nonalcoholic Steatohepatitis
por: Narayanan, Sowmya, et al.
Publicado: (2016)

Betel Chewing and Nonalcoholic Steatohepatitis
por: Bleibel, Wissam, et al.
Publicado: (2018)

The metabolic basis of nonalcoholic steatohepatitis
por: Chakravarthy, Manu V., et al.
Publicado: (2020)

Pathogenesis of Nonalcoholic Steatohepatitis: An Overview
por: Parthasarathy, Gopanandan, et al.
Publicado: (2020)

Insulinoma in Patient With Nonalcoholic Steatohepatitis
por: Cain, Daniel, et al.
Publicado: (2023)

Challenges and opportunities in nonalcoholic steatohepatitis
por: Wang, Xiaobo
Publicado: (2022)

Milk fat globule-epidermal growth factor 8 (MFG-E8) attenuates sepsis-induced acute kidney injury by inhibiting NF-κB signaling pathway
por: Zhao, Yang, et al.
Publicado: (2019)

MFG on track with Georgia plant upgrades
Publicado: (2020)

MFG-E8 Regulates Microglial Phagocytosis of Apoptotic Neurons
por: Fuller, Abby D., et al.
Publicado: (2008)

DCI after Aneurysmal Subarachnoid Hemorrhage Is Related to the Expression of MFG-E8
por: Chen, Xianjun, et al.
Publicado: (2021)

Adiponectin Inhibits NLRP3 Inflammasome Activation in Nonalcoholic Steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS Signaling Pathways
por: Dong, Zhixia, et al.
Publicado: (2020)

Subcutaneous injection of dendritic cells aggravates atherosclerosis in ApoE-knockout mice by activation of TLR4
por: Ye, Zhishuai, et al.
Publicado: (2017)

LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway
por: Zhong, Yu, et al.
Publicado: (2020)

Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis
por: Imajo, Kento, et al.
Publicado: (2013)

Soluble Endoglin as a Potential Biomarker of Nonalcoholic Steatohepatitis (NASH) Development, Participating in Aggravation of NASH-Related Changes in Mouse Liver
por: Igreja Sá, Ivone Cristina, et al.
Publicado: (2020)

Genetic Deficiency of Indoleamine 2,3-dioxygenase Aggravates Vascular but Not Liver Disease in a Nonalcoholic Steatohepatitis and Atherosclerosis Comorbidity Model
por: Arora, Aastha, et al.
Publicado: (2022)

Wilson's disease masquerading as nonalcoholic steatohepatitis
por: Mahmood, Sabina, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_drcvfdq5jd7fbtpquh6nf9bn27