Nervous system manifestations related to COVID-19 and their possible mechanisms

In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed that this disease is closely related to the nervous...

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Detalles Bibliográficos
Autores principales: Xie, Zhen, Hui, Hao, Zhao, Zhihan, Yu, Wenjin, Wu, Rui, Zhu, Yanzhao, Song, Yuan, Cao, Bingqing, Shi, Wenzhen, Zhao, Di, Zhao, Yunsong, Lv, Junchao, Yao, Qian, Duan, Yan, Li, Jingwen, Zhang, Haijun, Zhou, Linfu, Wang, Xiaotian, Tian, Ye, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236920/
https://www.ncbi.nlm.nih.gov/pubmed/35772604
http://dx.doi.org/10.1016/j.brainresbull.2022.06.014
Descripción
Sumario:In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed that this disease is closely related to the nervous system and has complex effects on the central nervous system (CNS) and peripheral nervous system (PNS). In this review, we summarize the effects and mechanisms of SARS-CoV-2 on the nervous system, including the pathways of invasion, direct and indirect effects, and associated neuropsychiatric diseases, to deepen our knowledge and understanding of the relationship between COVID-19 and the nervous system.

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