Nervous system manifestations related to COVID-19 and their possible mechanisms

In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed that this disease is closely related to the nervous...

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Autores principales: Xie, Zhen, Hui, Hao, Zhao, Zhihan, Yu, Wenjin, Wu, Rui, Zhu, Yanzhao, Song, Yuan, Cao, Bingqing, Shi, Wenzhen, Zhao, Di, Zhao, Yunsong, Lv, Junchao, Yao, Qian, Duan, Yan, Li, Jingwen, Zhang, Haijun, Zhou, Linfu, Wang, Xiaotian, Tian, Ye, Zhao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236920/
https://www.ncbi.nlm.nih.gov/pubmed/35772604
http://dx.doi.org/10.1016/j.brainresbull.2022.06.014
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author Xie, Zhen
Hui, Hao
Zhao, Zhihan
Yu, Wenjin
Wu, Rui
Zhu, Yanzhao
Song, Yuan
Cao, Bingqing
Shi, Wenzhen
Zhao, Di
Zhao, Yunsong
Lv, Junchao
Yao, Qian
Duan, Yan
Li, Jingwen
Zhang, Haijun
Zhou, Linfu
Wang, Xiaotian
Tian, Ye
Zhao, Gang
author_facet Xie, Zhen
Hui, Hao
Zhao, Zhihan
Yu, Wenjin
Wu, Rui
Zhu, Yanzhao
Song, Yuan
Cao, Bingqing
Shi, Wenzhen
Zhao, Di
Zhao, Yunsong
Lv, Junchao
Yao, Qian
Duan, Yan
Li, Jingwen
Zhang, Haijun
Zhou, Linfu
Wang, Xiaotian
Tian, Ye
Zhao, Gang
author_sort Xie, Zhen
collection PubMed
description In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed that this disease is closely related to the nervous system and has complex effects on the central nervous system (CNS) and peripheral nervous system (PNS). In this review, we summarize the effects and mechanisms of SARS-CoV-2 on the nervous system, including the pathways of invasion, direct and indirect effects, and associated neuropsychiatric diseases, to deepen our knowledge and understanding of the relationship between COVID-19 and the nervous system.
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spelling pubmed-92369202022-06-28 Nervous system manifestations related to COVID-19 and their possible mechanisms Xie, Zhen Hui, Hao Zhao, Zhihan Yu, Wenjin Wu, Rui Zhu, Yanzhao Song, Yuan Cao, Bingqing Shi, Wenzhen Zhao, Di Zhao, Yunsong Lv, Junchao Yao, Qian Duan, Yan Li, Jingwen Zhang, Haijun Zhou, Linfu Wang, Xiaotian Tian, Ye Zhao, Gang Brain Res Bull Article In December 2019, the novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection broke. With the gradual deepening understanding of SARS-CoV-2 and COVID-19, researchers and clinicians noticed that this disease is closely related to the nervous system and has complex effects on the central nervous system (CNS) and peripheral nervous system (PNS). In this review, we summarize the effects and mechanisms of SARS-CoV-2 on the nervous system, including the pathways of invasion, direct and indirect effects, and associated neuropsychiatric diseases, to deepen our knowledge and understanding of the relationship between COVID-19 and the nervous system. The Authors. Published by Elsevier Inc. 2022-09 2022-06-28 /pmc/articles/PMC9236920/ /pubmed/35772604 http://dx.doi.org/10.1016/j.brainresbull.2022.06.014 Text en © 2022 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Xie, Zhen
Hui, Hao
Zhao, Zhihan
Yu, Wenjin
Wu, Rui
Zhu, Yanzhao
Song, Yuan
Cao, Bingqing
Shi, Wenzhen
Zhao, Di
Zhao, Yunsong
Lv, Junchao
Yao, Qian
Duan, Yan
Li, Jingwen
Zhang, Haijun
Zhou, Linfu
Wang, Xiaotian
Tian, Ye
Zhao, Gang
Nervous system manifestations related to COVID-19 and their possible mechanisms
title Nervous system manifestations related to COVID-19 and their possible mechanisms
title_full Nervous system manifestations related to COVID-19 and their possible mechanisms
title_fullStr Nervous system manifestations related to COVID-19 and their possible mechanisms
title_full_unstemmed Nervous system manifestations related to COVID-19 and their possible mechanisms
title_short Nervous system manifestations related to COVID-19 and their possible mechanisms
title_sort nervous system manifestations related to covid-19 and their possible mechanisms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236920/
https://www.ncbi.nlm.nih.gov/pubmed/35772604
http://dx.doi.org/10.1016/j.brainresbull.2022.06.014
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