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Let-7a mimic transfection reduces chemotherapy-induced damage in a mouse ovarian transplantation model

Pharmacological approaches offer a non-invasive and promising option for fertility preservation in young female cancer patients undergoing gonadotoxic therapy. The GnRH-agonists are the only clinically available drugs in this indication, but their use and mechanisms of protection are still controver...

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Detalles Bibliográficos
Autores principales: Alexandri, Chrysanthi, Van Den Steen, Geraldine, Demeestere, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237019/
https://www.ncbi.nlm.nih.gov/pubmed/35760952
http://dx.doi.org/10.1038/s41598-022-14926-z