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Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

The global coronavirus disease 2019 (COVID-19) pandemic has claimed more than 5 million lives. Emerging variants of concern (VOCs) continually challenge viral control. Directing vaccine-induced humoral and cell-mediated responses to mucosal surfaces may enhance vaccine efficacy. Here we investigate...

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Detalles Bibliográficos
Autores principales: Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce, Parzych, Elizabeth M., Ali, Ali R., Frase, Drew, Moffat, Estella, Embury-Hyatt, Carissa, Smith, Trevor R.F., Broderick, Kate E., Humeau, Laurent, Kobasa, Darwyn, Patel, Ami, Kulp, Daniel W., Weiner, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237025/
https://www.ncbi.nlm.nih.gov/pubmed/35839767
http://dx.doi.org/10.1016/j.xcrm.2022.100693