Cargando…

The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications

BACKGROUND: The reduction in SARS-CoV-2 transmission facilitated by mobile contact tracing applications (apps) depends both on the proportion of relevant contacts notified and on the probability that those contacts quarantine after notification. The proportion of relevant contacts notified depends u...

Descripción completa

Detalles Bibliográficos
Autores principales: Leng, Trystan, Hill, Edward M., Keeling, Matt J., Tildesley, Michael J., Thompson, Robin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237034/
https://www.ncbi.nlm.nih.gov/pubmed/35774530
http://dx.doi.org/10.1038/s43856-022-00143-2
_version_ 1784736676698914816
author Leng, Trystan
Hill, Edward M.
Keeling, Matt J.
Tildesley, Michael J.
Thompson, Robin N.
author_facet Leng, Trystan
Hill, Edward M.
Keeling, Matt J.
Tildesley, Michael J.
Thompson, Robin N.
author_sort Leng, Trystan
collection PubMed
description BACKGROUND: The reduction in SARS-CoV-2 transmission facilitated by mobile contact tracing applications (apps) depends both on the proportion of relevant contacts notified and on the probability that those contacts quarantine after notification. The proportion of relevant contacts notified depends upon the number of days preceding an infector’s positive test that their contacts are notified, which we refer to as an app’s notification window. METHODS: We use an epidemiological model of SARS-CoV-2 transmission that captures the profile of infection to consider the trade-off between notification window length and active app use. We focus on 5-day and 2-day windows, the notification windows of the NHS COVID-19 app in England and Wales before and after 2nd August 2021, respectively. RESULTS: Our analyses show that at the same level of active app use, 5-day windows result in larger reductions in transmission than 2-day windows. However, short notification windows can be more effective at reducing transmission if they are associated with higher levels of active app use and adherence to isolation upon notification. CONCLUSIONS: Our results demonstrate the importance of understanding adherence to interventions when setting notification windows for COVID-19 contact tracing apps.
format Online
Article
Text
id pubmed-9237034
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-92370342022-06-29 The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications Leng, Trystan Hill, Edward M. Keeling, Matt J. Tildesley, Michael J. Thompson, Robin N. Commun Med (Lond) Article BACKGROUND: The reduction in SARS-CoV-2 transmission facilitated by mobile contact tracing applications (apps) depends both on the proportion of relevant contacts notified and on the probability that those contacts quarantine after notification. The proportion of relevant contacts notified depends upon the number of days preceding an infector’s positive test that their contacts are notified, which we refer to as an app’s notification window. METHODS: We use an epidemiological model of SARS-CoV-2 transmission that captures the profile of infection to consider the trade-off between notification window length and active app use. We focus on 5-day and 2-day windows, the notification windows of the NHS COVID-19 app in England and Wales before and after 2nd August 2021, respectively. RESULTS: Our analyses show that at the same level of active app use, 5-day windows result in larger reductions in transmission than 2-day windows. However, short notification windows can be more effective at reducing transmission if they are associated with higher levels of active app use and adherence to isolation upon notification. CONCLUSIONS: Our results demonstrate the importance of understanding adherence to interventions when setting notification windows for COVID-19 contact tracing apps. Nature Publishing Group UK 2022-06-27 /pmc/articles/PMC9237034/ /pubmed/35774530 http://dx.doi.org/10.1038/s43856-022-00143-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Leng, Trystan
Hill, Edward M.
Keeling, Matt J.
Tildesley, Michael J.
Thompson, Robin N.
The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications
title The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications
title_full The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications
title_fullStr The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications
title_full_unstemmed The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications
title_short The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications
title_sort effect of notification window length on the epidemiological impact of covid-19 contact tracing mobile applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237034/
https://www.ncbi.nlm.nih.gov/pubmed/35774530
http://dx.doi.org/10.1038/s43856-022-00143-2
work_keys_str_mv AT lengtrystan theeffectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT hilledwardm theeffectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT keelingmattj theeffectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT tildesleymichaelj theeffectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT thompsonrobinn theeffectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT lengtrystan effectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT hilledwardm effectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT keelingmattj effectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT tildesleymichaelj effectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications
AT thompsonrobinn effectofnotificationwindowlengthontheepidemiologicalimpactofcovid19contacttracingmobileapplications