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Efficient expansion of rare human circulating hematopoietic stem/progenitor cells in steady-state blood using a polypeptide-forming 3D culture

Although widely applied in treating hematopoietic malignancies, transplantation of hematopoietic stem/progenitor cells (HSPCs) is impeded by HSPC shortage. Whether circulating HSPCs (cHSPCs) in steady-state blood could be used as an alternative source remains largely elusive. Here we develop a three...

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Detalles Bibliográficos
Autores principales: Xu, Yulin, Zeng, Xiangjun, Zhang, Mingming, Wang, Binsheng, Guo, Xin, Shan, Wei, Cai, Shuyang, Luo, Qian, Li, Honghu, Li, Xia, Li, Xue, Zhang, Hao, Wang, Limengmeng, Lin, Yu, Liu, Lizhen, Li, Yanwei, Zhang, Meng, Yu, Xiaohong, Qian, Pengxu, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237197/
https://www.ncbi.nlm.nih.gov/pubmed/35230662
http://dx.doi.org/10.1007/s13238-021-00900-4