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Mechanisms of Direct and Indirect Presentation of Self-Antigens in the Thymus
The inevitability of evolution of the adaptive immune system with its mechanism of randomly rearranging segments of the T cell receptor (TCR) gene is the generation of self-reactive clones. For the sake of prevention of autoimmunity, these clones must be eliminated from the pool of circulating T cel...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237256/ https://www.ncbi.nlm.nih.gov/pubmed/35774801 http://dx.doi.org/10.3389/fimmu.2022.926625 |