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Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses

BACKGROUND: This study investigated the utility of depression and anxiety symptom screening in patients scheduled for total knee arthroplasty to examine differences in active symptoms according to patients’ mental health diagnoses and associated prescription medications. MATERIAL AND METHODS: This c...

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Autores principales: Lippold, Brandon, Tarkunde, Yash R., Cheng, Abby L., Hannon, Charles P., Adelani, Muyibat A., Calfee, Ryan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237258/
https://www.ncbi.nlm.nih.gov/pubmed/35774874
http://dx.doi.org/10.1016/j.artd.2022.01.032
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author Lippold, Brandon
Tarkunde, Yash R.
Cheng, Abby L.
Hannon, Charles P.
Adelani, Muyibat A.
Calfee, Ryan P.
author_facet Lippold, Brandon
Tarkunde, Yash R.
Cheng, Abby L.
Hannon, Charles P.
Adelani, Muyibat A.
Calfee, Ryan P.
author_sort Lippold, Brandon
collection PubMed
description BACKGROUND: This study investigated the utility of depression and anxiety symptom screening in patients scheduled for total knee arthroplasty to examine differences in active symptoms according to patients’ mental health diagnoses and associated prescription medications. MATERIAL AND METHODS: This cross-sectional study analyzed 594 patients scheduled for total knee arthroplasty at a tertiary practice between June 2018 and December 2018. Patients completed Patient-Reported Outcomes Measurements Information System (PROMIS) Depression and Anxiety Computerized Adaptive Tests in clinic quantifying active symptoms. Mental health diagnoses and associated medications were extracted from health records. Statistical analysis assessed between-group differences in mean PROMIS scores and the prevalence of heightened depressive and anxiety symptoms. RESULTS: Multivariable linear regression modeling demonstrated that being diagnosed with depression without medication (β 7.1; P < .001) and with medication (β 8.6; P < .001) were each associated with higher PROMIS Depression scores. Similar modeling demonstrated that patients diagnosed with anxiety and prescribed an anxiolytic (β 8.4; P < .001) were associated with higher PROMIS Anxiety scores than undiagnosed patients. Eighty-six (15%) patients experienced heightened anxiety and/or depressive symptoms. Heightened depressive symptoms were more prevalent among those diagnosed with depression (19% without medication, 24% with antidepressant vs 5% undiagnosed: P < .001). Heightened anxiety symptoms were most prevalent among those diagnosed with anxiety and on anxiolytic medication (25% vs 7% diagnosed with anxiety without medication, 8% undiagnosed: P < .001). CONCLUSION: One in seven arthroplasty patients screened reported heightened depressive and/or anxiety symptoms. Despite the majority of arthroplasty patients on antidepressants and anxiolytics having symptoms controlled, these patients remain at increased risk of heightened active symptoms.
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spelling pubmed-92372582022-06-29 Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses Lippold, Brandon Tarkunde, Yash R. Cheng, Abby L. Hannon, Charles P. Adelani, Muyibat A. Calfee, Ryan P. Arthroplast Today Original Research BACKGROUND: This study investigated the utility of depression and anxiety symptom screening in patients scheduled for total knee arthroplasty to examine differences in active symptoms according to patients’ mental health diagnoses and associated prescription medications. MATERIAL AND METHODS: This cross-sectional study analyzed 594 patients scheduled for total knee arthroplasty at a tertiary practice between June 2018 and December 2018. Patients completed Patient-Reported Outcomes Measurements Information System (PROMIS) Depression and Anxiety Computerized Adaptive Tests in clinic quantifying active symptoms. Mental health diagnoses and associated medications were extracted from health records. Statistical analysis assessed between-group differences in mean PROMIS scores and the prevalence of heightened depressive and anxiety symptoms. RESULTS: Multivariable linear regression modeling demonstrated that being diagnosed with depression without medication (β 7.1; P < .001) and with medication (β 8.6; P < .001) were each associated with higher PROMIS Depression scores. Similar modeling demonstrated that patients diagnosed with anxiety and prescribed an anxiolytic (β 8.4; P < .001) were associated with higher PROMIS Anxiety scores than undiagnosed patients. Eighty-six (15%) patients experienced heightened anxiety and/or depressive symptoms. Heightened depressive symptoms were more prevalent among those diagnosed with depression (19% without medication, 24% with antidepressant vs 5% undiagnosed: P < .001). Heightened anxiety symptoms were most prevalent among those diagnosed with anxiety and on anxiolytic medication (25% vs 7% diagnosed with anxiety without medication, 8% undiagnosed: P < .001). CONCLUSION: One in seven arthroplasty patients screened reported heightened depressive and/or anxiety symptoms. Despite the majority of arthroplasty patients on antidepressants and anxiolytics having symptoms controlled, these patients remain at increased risk of heightened active symptoms. Elsevier 2022-03-02 /pmc/articles/PMC9237258/ /pubmed/35774874 http://dx.doi.org/10.1016/j.artd.2022.01.032 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Lippold, Brandon
Tarkunde, Yash R.
Cheng, Abby L.
Hannon, Charles P.
Adelani, Muyibat A.
Calfee, Ryan P.
Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses
title Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses
title_full Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses
title_fullStr Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses
title_full_unstemmed Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses
title_short Depression and Anxiety Screening Identifies Patients That may Benefit From Treatment Regardless of Existing Diagnoses
title_sort depression and anxiety screening identifies patients that may benefit from treatment regardless of existing diagnoses
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237258/
https://www.ncbi.nlm.nih.gov/pubmed/35774874
http://dx.doi.org/10.1016/j.artd.2022.01.032
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