Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment

Cerebral small vessel disease (CSVD) is the most common chronic vascular disease involving the whole brain. Great progress has been made in clinical imaging, pathological mechanism, and treatment of CSVD, but many problems remain. Clarifying the current research dilemmas and future development direc...

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Autores principales: Ren, Beida, Tan, Ling, Song, Yuebo, Li, Danxi, Xue, Bingjie, Lai, Xinxing, Gao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237477/
https://www.ncbi.nlm.nih.gov/pubmed/35775047
http://dx.doi.org/10.3389/fneur.2022.843953
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author Ren, Beida
Tan, Ling
Song, Yuebo
Li, Danxi
Xue, Bingjie
Lai, Xinxing
Gao, Ying
author_facet Ren, Beida
Tan, Ling
Song, Yuebo
Li, Danxi
Xue, Bingjie
Lai, Xinxing
Gao, Ying
author_sort Ren, Beida
collection PubMed
description Cerebral small vessel disease (CSVD) is the most common chronic vascular disease involving the whole brain. Great progress has been made in clinical imaging, pathological mechanism, and treatment of CSVD, but many problems remain. Clarifying the current research dilemmas and future development direction of CSVD can provide new ideas for both basic and clinical research. In this review, the risk factors, biological markers, pathological mechanisms, and the treatment of CSVD will be systematically illustrated to provide the current research status of CSVD. The future development direction of CSVD will be elucidated by summarizing the research difficulties.
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spelling pubmed-92374772022-06-29 Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment Ren, Beida Tan, Ling Song, Yuebo Li, Danxi Xue, Bingjie Lai, Xinxing Gao, Ying Front Neurol Neurology Cerebral small vessel disease (CSVD) is the most common chronic vascular disease involving the whole brain. Great progress has been made in clinical imaging, pathological mechanism, and treatment of CSVD, but many problems remain. Clarifying the current research dilemmas and future development direction of CSVD can provide new ideas for both basic and clinical research. In this review, the risk factors, biological markers, pathological mechanisms, and the treatment of CSVD will be systematically illustrated to provide the current research status of CSVD. The future development direction of CSVD will be elucidated by summarizing the research difficulties. Frontiers Media S.A. 2022-06-14 /pmc/articles/PMC9237477/ /pubmed/35775047 http://dx.doi.org/10.3389/fneur.2022.843953 Text en Copyright © 2022 Ren, Tan, Song, Li, Xue, Lai and Gao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Ren, Beida
Tan, Ling
Song, Yuebo
Li, Danxi
Xue, Bingjie
Lai, Xinxing
Gao, Ying
Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment
title Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment
title_full Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment
title_fullStr Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment
title_full_unstemmed Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment
title_short Cerebral Small Vessel Disease: Neuroimaging Features, Biochemical Markers, Influencing Factors, Pathological Mechanism and Treatment
title_sort cerebral small vessel disease: neuroimaging features, biochemical markers, influencing factors, pathological mechanism and treatment
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237477/
https://www.ncbi.nlm.nih.gov/pubmed/35775047
http://dx.doi.org/10.3389/fneur.2022.843953
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