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Positional weight matrices have sufficient prediction power for analysis of noncoding variants

The position weight matrix, also called the position-specific scoring matrix, is the commonly accepted model to quantify the specificity of transcription factor binding to DNA. Position weight matrices are used in thousands of projects and software tools in regulatory genomics, including computation...

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Detalles Bibliográficos
Autores principales: Boytsov, Alexandr, Abramov, Sergey, Makeev, Vsevolod J., Kulakovskiy, Ivan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237556/
https://www.ncbi.nlm.nih.gov/pubmed/35811788
http://dx.doi.org/10.12688/f1000research.75471.3