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Positional weight matrices have sufficient prediction power for analysis of noncoding variants
The position weight matrix, also called the position-specific scoring matrix, is the commonly accepted model to quantify the specificity of transcription factor binding to DNA. Position weight matrices are used in thousands of projects and software tools in regulatory genomics, including computation...
Autores principales: | Boytsov, Alexandr, Abramov, Sergey, Makeev, Vsevolod J., Kulakovskiy, Ivan V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237556/ https://www.ncbi.nlm.nih.gov/pubmed/35811788 http://dx.doi.org/10.12688/f1000research.75471.3 |
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