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Conditional generative modeling for de novo protein design with hierarchical functions

MOTIVATION: Protein design has become increasingly important for medical and biotechnological applications. Because of the complex mechanisms underlying protein formation, the creation of a novel protein requires tedious and time-consuming computational or experimental protocols. At the same time, m...

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Detalles Bibliográficos
Autores principales: Kucera, Tim, Togninalli, Matteo, Meng-Papaxanthos, Laetitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237736/
https://www.ncbi.nlm.nih.gov/pubmed/35639661
http://dx.doi.org/10.1093/bioinformatics/btac353