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Production of Lentiviral Vectors Using a HEK-293 Producer Cell Line and Advanced Perfusion Processing

The field of lentiviral vector (LV) production continues to face challenges in large-scale manufacturing, specifically regarding producing enough vectors to meet the demand for treating patients as well as producing high and consistent quality of vectors for efficient dosing. Two areas of interest a...

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Detalles Bibliográficos
Autores principales: Tran, Michelle Yen, Kamen, Amine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237754/
https://www.ncbi.nlm.nih.gov/pubmed/35774066
http://dx.doi.org/10.3389/fbioe.2022.887716