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Development of a T cell-redirecting bispecific antibody targeting B-cell maturation antigen for the suppression of multiple myeloma cell growth

BACKGROUND: Multiple myeloma (MM) is the second most common hematological malignancy. It has emerged as one of the next possible hematological diseases amenable to immunotherapy. B-cell maturation antigen (BCMA), a member of the tumor necrosis factor receptor superfamily, is highly expressed in MM c...

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Detalles Bibliográficos
Autores principales:	Huo, Jianxin, Huang, Yuhan, Zheng, Ziying, Tay, Xin Ni, Mahfut, Farouq Bin, Zhang, Wei, Lam, Kong-Peng, Yang, Yuansheng, Xu, Shengli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Bispecific Antibody CMC
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237814/ https://www.ncbi.nlm.nih.gov/pubmed/35774245 http://dx.doi.org/10.1093/abt/tbac012

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