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Gait analysis under the lens of statistical physics

Human gait is a fundamental activity, essential for the survival of the individual, and an emergent property of the interactions between complex physical and cognitive processes. Gait is altered in many situations, due both to external constraints, as e.g. paced walk, and to physical and neurologica...

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Autores principales: Zanin, Massimiliano, Olivares, Felipe, Pulido-Valdeolivas, Irene, Rausell, Estrella, Gomez-Andres, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237948/
https://www.ncbi.nlm.nih.gov/pubmed/35782747
http://dx.doi.org/10.1016/j.csbj.2022.06.022
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author Zanin, Massimiliano
Olivares, Felipe
Pulido-Valdeolivas, Irene
Rausell, Estrella
Gomez-Andres, David
author_facet Zanin, Massimiliano
Olivares, Felipe
Pulido-Valdeolivas, Irene
Rausell, Estrella
Gomez-Andres, David
author_sort Zanin, Massimiliano
collection PubMed
description Human gait is a fundamental activity, essential for the survival of the individual, and an emergent property of the interactions between complex physical and cognitive processes. Gait is altered in many situations, due both to external constraints, as e.g. paced walk, and to physical and neurological pathologies. Its study is therefore important as a way of improving the quality of life of patients, but also as a door to understanding the inner working of the human nervous system. In this review we explore how four statistical physics concepts have been used to characterise normal and pathological gait: entropy, maximum Lyapunov exponent, multi-fractal analysis and irreversibility. Beyond some basic definitions, we present the main results that have been obtained in this field, as well as a discussion of the main limitations researchers have dealt and will have to deal with. We finally conclude with some biomedical considerations and avenues for further development.
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spelling pubmed-92379482022-07-01 Gait analysis under the lens of statistical physics Zanin, Massimiliano Olivares, Felipe Pulido-Valdeolivas, Irene Rausell, Estrella Gomez-Andres, David Comput Struct Biotechnol J Review Human gait is a fundamental activity, essential for the survival of the individual, and an emergent property of the interactions between complex physical and cognitive processes. Gait is altered in many situations, due both to external constraints, as e.g. paced walk, and to physical and neurological pathologies. Its study is therefore important as a way of improving the quality of life of patients, but also as a door to understanding the inner working of the human nervous system. In this review we explore how four statistical physics concepts have been used to characterise normal and pathological gait: entropy, maximum Lyapunov exponent, multi-fractal analysis and irreversibility. Beyond some basic definitions, we present the main results that have been obtained in this field, as well as a discussion of the main limitations researchers have dealt and will have to deal with. We finally conclude with some biomedical considerations and avenues for further development. Research Network of Computational and Structural Biotechnology 2022-06-18 /pmc/articles/PMC9237948/ /pubmed/35782747 http://dx.doi.org/10.1016/j.csbj.2022.06.022 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zanin, Massimiliano
Olivares, Felipe
Pulido-Valdeolivas, Irene
Rausell, Estrella
Gomez-Andres, David
Gait analysis under the lens of statistical physics
title Gait analysis under the lens of statistical physics
title_full Gait analysis under the lens of statistical physics
title_fullStr Gait analysis under the lens of statistical physics
title_full_unstemmed Gait analysis under the lens of statistical physics
title_short Gait analysis under the lens of statistical physics
title_sort gait analysis under the lens of statistical physics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9237948/
https://www.ncbi.nlm.nih.gov/pubmed/35782747
http://dx.doi.org/10.1016/j.csbj.2022.06.022
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