Cargando…

Vitamin D level in relation to depression symptoms during adolescence

BACKGROUND: This study aimed to investigate the association between 25-hydroxyvitamin D (25(OH)D) and depression symptoms among adolescents in Kuwait, a country with a high prevalence of vitamin D deficiency. METHODS: A school based cross-sectional study was conducted on randomly selected 704 adoles...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Sabah, Reem, Al-Taiar, Abdullah, Shaban, Lemia, Albatineh, Ahmed N., Sharaf Alddin, Reem, Durgampudi, Praveen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238117/
https://www.ncbi.nlm.nih.gov/pubmed/35761369
http://dx.doi.org/10.1186/s13034-022-00489-4
_version_ 1784736958754324480
author Al-Sabah, Reem
Al-Taiar, Abdullah
Shaban, Lemia
Albatineh, Ahmed N.
Sharaf Alddin, Reem
Durgampudi, Praveen K.
author_facet Al-Sabah, Reem
Al-Taiar, Abdullah
Shaban, Lemia
Albatineh, Ahmed N.
Sharaf Alddin, Reem
Durgampudi, Praveen K.
author_sort Al-Sabah, Reem
collection PubMed
description BACKGROUND: This study aimed to investigate the association between 25-hydroxyvitamin D (25(OH)D) and depression symptoms among adolescents in Kuwait, a country with a high prevalence of vitamin D deficiency. METHODS: A school based cross-sectional study was conducted on randomly selected 704 adolescents in middle schools. Data on depression symptoms were collected using the Children’s Depression Inventory (CDI). Data on covariates were collected from the parents by self-administered questionnaire and from adolescents by face-to-face interview. Blood samples were analyzed in an accredited laboratory; and 25(OH)D was measured using liquid chromatography-tandem mass spectrometry. RESULTS: Of 704 adolescents, 94 (13.35%; 95%CI:10.35–17.06%) had depression symptom (a score of 19 or more on the CDI). There was no significant difference in the median CDI score between different vitamin D status (p = 0.366). There was also no significant correlation between serum 25(OH)D concentration and CDI score (Spearman’s rank correlation = 0.01; p = 0.825).There was no significant association between 25(OH)D and depression symptoms whether 25(OH)D was fitted as a continuous variable (crude odds ratio (OR) 0 .99 [95%CI: 0.98, 1.01], p = 0.458 and adjusted OR 1.01 [95%CI: 0.99, 1.02], p = 0.233), categorical variable as per acceptable cut-of points (crude analysis p = 0.376 and adjusted analysis p = 0.736), or categorical variable as quartiles (crude analysis p = 0.760 and adjusted analysis p = 0.549). CONCLUSION: Vitamin D status does not seem to be associated with depression symptoms among adolescents in our setting. Nevertheless, it is important to have sufficient vitamin D levels during adolescence for several other health benefits.
format Online
Article
Text
id pubmed-9238117
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-92381172022-06-29 Vitamin D level in relation to depression symptoms during adolescence Al-Sabah, Reem Al-Taiar, Abdullah Shaban, Lemia Albatineh, Ahmed N. Sharaf Alddin, Reem Durgampudi, Praveen K. Child Adolesc Psychiatry Ment Health Research BACKGROUND: This study aimed to investigate the association between 25-hydroxyvitamin D (25(OH)D) and depression symptoms among adolescents in Kuwait, a country with a high prevalence of vitamin D deficiency. METHODS: A school based cross-sectional study was conducted on randomly selected 704 adolescents in middle schools. Data on depression symptoms were collected using the Children’s Depression Inventory (CDI). Data on covariates were collected from the parents by self-administered questionnaire and from adolescents by face-to-face interview. Blood samples were analyzed in an accredited laboratory; and 25(OH)D was measured using liquid chromatography-tandem mass spectrometry. RESULTS: Of 704 adolescents, 94 (13.35%; 95%CI:10.35–17.06%) had depression symptom (a score of 19 or more on the CDI). There was no significant difference in the median CDI score between different vitamin D status (p = 0.366). There was also no significant correlation between serum 25(OH)D concentration and CDI score (Spearman’s rank correlation = 0.01; p = 0.825).There was no significant association between 25(OH)D and depression symptoms whether 25(OH)D was fitted as a continuous variable (crude odds ratio (OR) 0 .99 [95%CI: 0.98, 1.01], p = 0.458 and adjusted OR 1.01 [95%CI: 0.99, 1.02], p = 0.233), categorical variable as per acceptable cut-of points (crude analysis p = 0.376 and adjusted analysis p = 0.736), or categorical variable as quartiles (crude analysis p = 0.760 and adjusted analysis p = 0.549). CONCLUSION: Vitamin D status does not seem to be associated with depression symptoms among adolescents in our setting. Nevertheless, it is important to have sufficient vitamin D levels during adolescence for several other health benefits. BioMed Central 2022-06-27 /pmc/articles/PMC9238117/ /pubmed/35761369 http://dx.doi.org/10.1186/s13034-022-00489-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Al-Sabah, Reem
Al-Taiar, Abdullah
Shaban, Lemia
Albatineh, Ahmed N.
Sharaf Alddin, Reem
Durgampudi, Praveen K.
Vitamin D level in relation to depression symptoms during adolescence
title Vitamin D level in relation to depression symptoms during adolescence
title_full Vitamin D level in relation to depression symptoms during adolescence
title_fullStr Vitamin D level in relation to depression symptoms during adolescence
title_full_unstemmed Vitamin D level in relation to depression symptoms during adolescence
title_short Vitamin D level in relation to depression symptoms during adolescence
title_sort vitamin d level in relation to depression symptoms during adolescence
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9238117/
https://www.ncbi.nlm.nih.gov/pubmed/35761369
http://dx.doi.org/10.1186/s13034-022-00489-4
work_keys_str_mv AT alsabahreem vitamindlevelinrelationtodepressionsymptomsduringadolescence
AT altaiarabdullah vitamindlevelinrelationtodepressionsymptomsduringadolescence
AT shabanlemia vitamindlevelinrelationtodepressionsymptomsduringadolescence
AT albatinehahmedn vitamindlevelinrelationtodepressionsymptomsduringadolescence
AT sharafalddinreem vitamindlevelinrelationtodepressionsymptomsduringadolescence
AT durgampudipraveenk vitamindlevelinrelationtodepressionsymptomsduringadolescence